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Our research focus is to develop and test experimental and computational strategies for high throughput structure determination of proteins by X-ray crystallography and NMR methods and to apply these strategies to scan the entire genome of an organism at a rapid pace.  The eukaryotic organisms, Caenorhabditis elegans, Homo sapiens and an ancestrally-related prokaryotic microorganism having a small genome, Pyrococcus furiosus, are selected as representative genomes.

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